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AAALAC International Inc aaalac-approved facility
Aaalac Approved Facility, supplied by AAALAC International Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/aaalac-approved+facility/aaalac+approved+facility/pmc12274407-241-27-27
Average 90 stars, based on 1 article reviews
aaalac-approved facility - by Bioz Stars, 2026-09
90/100 stars

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In Vivo:

Article Title: Deep-tissue high-sensitivity multimodal imaging and optogenetic manipulation enabled by biliverdin reductase knockout.
Article Snippet: All procedures with animals were performed in an AAALAC-approved facility and received ethical approval from the Institutional Animal Care and Use Committee of the Albert Einstein College of Medicine (protocol 00001050) and Duke University (protocol A203-22-12).

Article Title: Sex bias determines MERS-CoV infection outcomes in a mouse model of differential pathogenicity
Article Snippet: Experiments were performed according to the guidelines of the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) and were carried out by certified staff in an AAALAC-approved facility.

Article Title: Maternal Undernutrition Exacerbates Effects of Ambient Heat During Pregnancy in Mice.
Article Snippet: Background: Undernutrition in women of childbearing age increases the risk of fetal growth 1 restriction and poor infant development.. A rise in ambient temperature is thought to exacerbate the 2 effects of undernutrition.. However, few mechanistic studies exist to examine the interactions 3 between maternal nutritional status and ambient temperature on fetal growth.

Article Title: A murine model lacking Lyst recapitulates Chediak-Higashi syndrome with an earlier-onset neurodegenerative phenotype
Article Snippet: All animals were housed in a pathogen-free environment with food and water supplied ad libitum under a 12 h light/dark cycle (from 06:00 to 18:00) in an AAALAC-approved facility following National Institutes of Health (NIH) and NHGRI ACUC-approved guidelines.

Article Title: Insights into the renal pathophysiology in Hermansky-Pudlak syndrome-1 from urinary extracellular vesicle proteomics and a new mouse model.
Article Snippet: Edited by Lukas Alfons Huber Hermansky-Pudlak syndrome type 1 (HPS-1) is a rare, autosomal recessive disorder caused by defects in the biogenesis of lysosome-related organelles complex-3 (BLOC-3).. Impaired kidney function is among its clinical manifestations.. To investigate HPS-1 renal involvement, we employed 1D-gel-LC– MS/MS and compared the protein composition of urinary extracellular vesicles (uEVs) from HPS-1 patients to normal control individuals.

Article Title: Neuropathic pain has sex‐specific effects on oxycodone‐seeking and non‐drug‐seeking ensemble neurons in the dorsomedial prefrontal cortex of mice
Article Snippet: Mice were kept in a 12 h reverse light cycle (0730‐1930) in an AAALAC‐approved facility.

Article Title: Therapeutic use of mitochondria and combined mitochondrial agents
Article Snippet: In Vivo Transplantation of ECFCs into Immunodeficient Nude Mice Animal experiments were conducted under a protocol approved by the Institutional Animal Care and Use Committee at Children's Hospital Boston in an AAALAC-approved facility.

Article Title: Effects of chronic ethanol exposure on dorsal medial striatal neurons receiving convergent inputs from the orbitofrontal cortex and basolateral amygdala.
Article Snippet: Alcohol use disorder is associated with altered function of cortical-amygdala-striatal circuits such as the orbitofrontal cortex (OFC), basolateral amygdala (BLA) and their connections to the dorsal medial striatum (DMS) shown to be involved in goal-directed actions.. Using retrobead tracing, we previously reported enhanced excitability of DMS-projecting OFC neurons in mice following 3-to-7-day withdrawal from chronic intermittent ethanol (CIE) exposure.. In the same animals, spiking of DMS-projecting BLA neurons was decreased at 3-days post-withdrawal followed by an increase in firing at 7and 14-days.

Transplantation Assay:

Article Title: Deep-tissue high-sensitivity multimodal imaging and optogenetic manipulation enabled by biliverdin reductase knockout.
Article Snippet: All procedures with animals were performed in an AAALAC-approved facility and received ethical approval from the Institutional Animal Care and Use Committee of the Albert Einstein College of Medicine (protocol 00001050) and Duke University (protocol A203-22-12).

Article Title: Sex bias determines MERS-CoV infection outcomes in a mouse model of differential pathogenicity
Article Snippet: Experiments were performed according to the guidelines of the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) and were carried out by certified staff in an AAALAC-approved facility.

Article Title: Maternal Undernutrition Exacerbates Effects of Ambient Heat During Pregnancy in Mice.
Article Snippet: Background: Undernutrition in women of childbearing age increases the risk of fetal growth 1 restriction and poor infant development.. A rise in ambient temperature is thought to exacerbate the 2 effects of undernutrition.. However, few mechanistic studies exist to examine the interactions 3 between maternal nutritional status and ambient temperature on fetal growth.

Article Title: A murine model lacking Lyst recapitulates Chediak-Higashi syndrome with an earlier-onset neurodegenerative phenotype
Article Snippet: All animals were housed in a pathogen-free environment with food and water supplied ad libitum under a 12 h light/dark cycle (from 06:00 to 18:00) in an AAALAC-approved facility following National Institutes of Health (NIH) and NHGRI ACUC-approved guidelines.

Article Title: Insights into the renal pathophysiology in Hermansky-Pudlak syndrome-1 from urinary extracellular vesicle proteomics and a new mouse model.
Article Snippet: Edited by Lukas Alfons Huber Hermansky-Pudlak syndrome type 1 (HPS-1) is a rare, autosomal recessive disorder caused by defects in the biogenesis of lysosome-related organelles complex-3 (BLOC-3).. Impaired kidney function is among its clinical manifestations.. To investigate HPS-1 renal involvement, we employed 1D-gel-LC– MS/MS and compared the protein composition of urinary extracellular vesicles (uEVs) from HPS-1 patients to normal control individuals.

Article Title: Neuropathic pain has sex‐specific effects on oxycodone‐seeking and non‐drug‐seeking ensemble neurons in the dorsomedial prefrontal cortex of mice
Article Snippet: Mice were kept in a 12 h reverse light cycle (0730‐1930) in an AAALAC‐approved facility.

Article Title: Therapeutic use of mitochondria and combined mitochondrial agents
Article Snippet: In Vivo Transplantation of ECFCs into Immunodeficient Nude Mice Animal experiments were conducted under a protocol approved by the Institutional Animal Care and Use Committee at Children's Hospital Boston in an AAALAC-approved facility.

Article Title: Effects of chronic ethanol exposure on dorsal medial striatal neurons receiving convergent inputs from the orbitofrontal cortex and basolateral amygdala.
Article Snippet: Alcohol use disorder is associated with altered function of cortical-amygdala-striatal circuits such as the orbitofrontal cortex (OFC), basolateral amygdala (BLA) and their connections to the dorsal medial striatum (DMS) shown to be involved in goal-directed actions.. Using retrobead tracing, we previously reported enhanced excitability of DMS-projecting OFC neurons in mice following 3-to-7-day withdrawal from chronic intermittent ethanol (CIE) exposure.. In the same animals, spiking of DMS-projecting BLA neurons was decreased at 3-days post-withdrawal followed by an increase in firing at 7and 14-days.

Mouse Assay:

Article Title: Deep-tissue high-sensitivity multimodal imaging and optogenetic manipulation enabled by biliverdin reductase knockout.
Article Snippet: All procedures with animals were performed in an AAALAC-approved facility and received ethical approval from the Institutional Animal Care and Use Committee of the Albert Einstein College of Medicine (protocol 00001050) and Duke University (protocol A203-22-12).

Article Title: Sex bias determines MERS-CoV infection outcomes in a mouse model of differential pathogenicity
Article Snippet: Experiments were performed according to the guidelines of the Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) and were carried out by certified staff in an AAALAC-approved facility.

Article Title: Maternal Undernutrition Exacerbates Effects of Ambient Heat During Pregnancy in Mice.
Article Snippet: Background: Undernutrition in women of childbearing age increases the risk of fetal growth 1 restriction and poor infant development.. A rise in ambient temperature is thought to exacerbate the 2 effects of undernutrition.. However, few mechanistic studies exist to examine the interactions 3 between maternal nutritional status and ambient temperature on fetal growth.

Article Title: A murine model lacking Lyst recapitulates Chediak-Higashi syndrome with an earlier-onset neurodegenerative phenotype
Article Snippet: All animals were housed in a pathogen-free environment with food and water supplied ad libitum under a 12 h light/dark cycle (from 06:00 to 18:00) in an AAALAC-approved facility following National Institutes of Health (NIH) and NHGRI ACUC-approved guidelines.

Article Title: Insights into the renal pathophysiology in Hermansky-Pudlak syndrome-1 from urinary extracellular vesicle proteomics and a new mouse model.
Article Snippet: Edited by Lukas Alfons Huber Hermansky-Pudlak syndrome type 1 (HPS-1) is a rare, autosomal recessive disorder caused by defects in the biogenesis of lysosome-related organelles complex-3 (BLOC-3).. Impaired kidney function is among its clinical manifestations.. To investigate HPS-1 renal involvement, we employed 1D-gel-LC– MS/MS and compared the protein composition of urinary extracellular vesicles (uEVs) from HPS-1 patients to normal control individuals.

Article Title: Neuropathic pain has sex‐specific effects on oxycodone‐seeking and non‐drug‐seeking ensemble neurons in the dorsomedial prefrontal cortex of mice
Article Snippet: Mice were kept in a 12 h reverse light cycle (0730‐1930) in an AAALAC‐approved facility.

Article Title: Therapeutic use of mitochondria and combined mitochondrial agents
Article Snippet: In Vivo Transplantation of ECFCs into Immunodeficient Nude Mice Animal experiments were conducted under a protocol approved by the Institutional Animal Care and Use Committee at Children's Hospital Boston in an AAALAC-approved facility.

Article Title: Effects of chronic ethanol exposure on dorsal medial striatal neurons receiving convergent inputs from the orbitofrontal cortex and basolateral amygdala.
Article Snippet: Alcohol use disorder is associated with altered function of cortical-amygdala-striatal circuits such as the orbitofrontal cortex (OFC), basolateral amygdala (BLA) and their connections to the dorsal medial striatum (DMS) shown to be involved in goal-directed actions.. Using retrobead tracing, we previously reported enhanced excitability of DMS-projecting OFC neurons in mice following 3-to-7-day withdrawal from chronic intermittent ethanol (CIE) exposure.. In the same animals, spiking of DMS-projecting BLA neurons was decreased at 3-days post-withdrawal followed by an increase in firing at 7and 14-days.



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